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However, the claims of wide-reaching health benefits persist, which Ayers also sees as concerning. There is also research, similarly in early stages, that suggests that high doses of CBD could have adverse effects on the liver and gastrointestinal systems, Cooper says. Beyond the FDA-approved uses, Cooper says some initial studies indicate CBD may be able to alleviate symptoms related to anxiety, schizophrenia and opioid use disorder. However, the the research is far from the level of FDA approval, and in those early studies, the dosage of CBD needed to treat the symptoms is much higher than what's available at dispensaries or online.